Surgeons are confronted daily with a myriad of skin pathology. Pyogeni
c and pseudopyogenic granulomas are certainly among the differential d
iagnoses to many nonhealing dermal lesions. This article revisits two
types of vascularized lesions that are perhaps part neoplastic and par
t inflammatory/reparative. The differences clinically between these tw
o types of lesions are few. The classical form generally is found alon
g mucosal surfaces and upper extremities. The pseudopyogenic granuloma
is more often found on the scalp and ears. Confirmation in their diag
noses is based strictly on their histological criteria. The management
of these two types of lesions is identical. Excisional biopsies for a
ll nonhealing lesions are warranted to rule out lesions with an ominou
s progression.