SUBSTITUTED THIAZOLIDINEDIONES AND THIO-IMIDAZOLIDINONES - SYNTHESIS,STRUCTURAL STUDY AND PHARMACOLOGICAL ACTIVITY

Authors
ALBUQUERQUE JFC ALBUQUERQUE A AZEVEDO CC THOMASSON F GALDINO LS CHANTEGREL J CATANHO MTJ PITTA IR LUUDUC C
Citation
Jfc. Albuquerque et al., SUBSTITUTED THIAZOLIDINEDIONES AND THIO-IMIDAZOLIDINONES - SYNTHESIS,STRUCTURAL STUDY AND PHARMACOLOGICAL ACTIVITY, Die Pharmazie, 50(6), 1995, pp. 387-389
Citations number
17
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Die Pharmazie → ACNP
ISSN journal
00317144
Volume
50
Issue
6
Year of publication
1995
Pages
387 - 389
Database
ISI
SICI code
0031-7144(1995)50:6<387:STAT-S>2.0.ZU;2-Q
Abstract
Synthesis and physico-chemical properties of six bromophenacyl)-5-aryl idene-thiazolidine-2,4-diones and eight orobenzyl)-5-arylidene-4-thio- imidazolidine-2-ones are described. These products were synthesized by an aldolisation-crotonisation reaction from aromatic aldehydes and 3- substituted thiazolidine-2,4-diones or 4-thio-imidazolidine-2-ones. Hy poglycemic and peripheral antinociceptive activities were investigated for these compounds.