EVALUATION OF ALUMINUM TRIS(2,6-DI-TERT-BUTYL-4-METHYLPHENOXIDE) (ATD) AS A LEWIS-ACID RECEPTOR

Authors
MARUOKA K IMOTO H YAMAMOTO H
Citation
K. Maruoka et al., EVALUATION OF ALUMINUM TRIS(2,6-DI-TERT-BUTYL-4-METHYLPHENOXIDE) (ATD) AS A LEWIS-ACID RECEPTOR, Synlett, (7), 1995, pp. 719
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
7
Year of publication
1995
Database
ISI
SICI code
0936-5214(1995):7<719:EOAT(>2.0.ZU;2-#
Abstract
Aluminum tris(2,6-di-tert-butyl-4-methylphenoxide) (ATD) has been succ essfully utilized as a Lewis acid receptor for effective blocking of c arbonyl functionality, thereby allowing (1) the conjugate addition of organolithium reagents to alpha,beta-unsaturated ketones, and (2) sele ctive reduction of more hindered ketones. The blocking ability of ATD is evaluated by comparison of the analogous Lewis acid receptors, ATPH and MAD.