ASYMMETRIC REACTIONS CATALYZED BY CHIRAL METAL-COMPLEXES .70. ASYMMETRIC HYDROGENATION OF CYCLIC KETIMINES CATALYZED BY IRIDIUM(I)-COMPLEXES OF BCPM AND ITS ANALOG

Authors
MORIMOTO T NAKAJIMA N ACHIWA K
Citation
T. Morimoto et al., ASYMMETRIC REACTIONS CATALYZED BY CHIRAL METAL-COMPLEXES .70. ASYMMETRIC HYDROGENATION OF CYCLIC KETIMINES CATALYZED BY IRIDIUM(I)-COMPLEXES OF BCPM AND ITS ANALOG, Synlett, (7), 1995, pp. 748-750
Citations number
43
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
7
Year of publication
1995
Pages
748 - 750
Database
ISI
SICI code
0936-5214(1995):7<748:ARCBCM>2.0.ZU;2-Q
Abstract
Modified pyrrolidinebisphosphines, BCPM (1a) and its analog MCCPM (1b) , were found to be more efficient ligands than the original BPPM (2a) in the iridium(I)-catalyzed asymmetric hydrogenation of imines in the presence of iodide. In particular, the modified ligands (1a,b) showed very high enantioselectivity of up to 91% ee in the hydrogenation of 2 ,3,3-trimethylindolenine (6) in the presence of bismuth(III) iodide.