DNAVIEW - A QUALITY ASSESSMENT-TOOL FOR THE VISUALIZATION OF LARGE SEQUENCED REGIONS

This communication describes DNA View, a graphical tool for the visual ization and printing of large nucleic acid sequences. DNA View uses co lor coding to compactly display genomic segments of up to 100 kb on a single printed page, The specific color schemes integrated into DNA Vi ew cart highlight 'local aggregate' properties of large segments of DN A. I have also incorporated a confidence expression for the assigned s equence. This is represented by base color intensity that is proportio nal to the number of times that base was sequenced. Areas of interest, such as exons, introns, repetitive elements and splice sites, can be emphasized using overlays. The colored image can be saved in a standar d TIFF image file format that may be imported and annotated by other a pplication software.