The authors describe the case of a highly stressed 36-year-old man who
experienced ten or more painful episodes per year of recurrent oral-l
ingual herpes simplex virus 1, which were only partially responsive to
acyclovir therapy for three years. A three-year diary of activities,
personal stresses, concurrent infections, local trauma, and other poss
ible psychogenic, somatogenic, and environmental events was used syste
matically to attempt to pair the stresses with the recurrent herpes ep
isodes. Chlorinated swimming pool water seems to have been the trigger
ing agent of the recurrent herpes simplex virus 1 episodes due to its
temporal correlation and the greater than twenty-four-month asymptomat
ic period after the patient discontinued swimming in chlorinated water
, but continued to swim in fresh and salt water, along with his normal
pursuit of all other activities and habits.