Nd. Ivanovska et al., IMMUNOMODULATORY ACTION OF PROPOLIS .6. INFLUENCE OF A WATER-SOLUBLE DERIVATIVE ON COMPLEMENT ACTIVITY IN-VIVO, Journal of ethnopharmacology, 47(3), 1995, pp. 145-147
The water soluble derivative (WSD) of propolis in a dose of 150 mg/kg
was administered intravenously (i.v.), intraperitoneally (i.p.) and or
ally (p.o.) to mice. The alteration of serum alternative pathway (AP)
complement level was observed. The WSD also influenced the process of
acute inflammation provoked by zymosan in mice. The effect was strongl
y dependent on the route of WSD administration.