This paper, which has been reviewed and approved by the Board of Direc
tors of the American Sleep Disorders Association, provides the backgro
und for the Standards of Practice Committee's parameters for the pract
ice of sleep medicine in North America. The 21 publications selected f
or this review describe 320 patients treated with oral appliances for
snoring and obstructive sleep apnea. The appliances modify the upper a
irway by changing the posture of the mandible and tongue. Despite cons
iderable variation in the design of these appliances, the clinical eff
ects are remarkably consistent. Snoring is improved and often eliminat
ed in almost all patients who use oral appliances. Obstructive sleep a
pnea improves in the majority of patients; the mean apnea-hypopnea ind
ex (AHI) in this group of patients was reduced from 47 to 19. Approxim
ately half of treated patients achieved an AHI of < 10; however, as ma
ny as 40% of those treated were left with significantly elevated AHIs.
Improvement in sleep quality and sleepiness reflects the effect on br
eathing. Limited follow-up data indicate that oral discomfort is a com
mon but tolerable side effect, that dental and mandibular complication
s appear to be uncommon and that longterm compliance varies from 50% t
o 100% of patients. Comparison of the risk and benefit of oral applian
ce therapy with the other available treatments suggests that oral appl
iances present a useful alternative to continuous positive airway pres
sure (CPAP), especially for patients with simple snoring and patients
with obstructive sleep apnea who cannot tolerate CPAP therapy.