SYNTHESIS OF PHENOLIC NATURAL-PRODUCTS USING PALLADIUM-CATALYZED COUPLING REACTIONS

Authors
BATES RW GABEL CJ JI JH RAMADEVI T
Citation
Rw. Bates et al., SYNTHESIS OF PHENOLIC NATURAL-PRODUCTS USING PALLADIUM-CATALYZED COUPLING REACTIONS, Tetrahedron, 51(30), 1995, pp. 8199-8212
Citations number
45
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
51
Issue
30
Year of publication
1995
Pages
8199 - 8212
Database
ISI
SICI code
0040-4020(1995)51:30<8199:SOPNUP>2.0.ZU;2-H
Abstract
Derivatives of 2,4-diiodophenol are shown to undergo palladium catalyz ed carbonylation and alkyne coupling reactions in excellent to moderat e yield and high regioselectivity. The scope of these reactions is exp lored. Palladium catalyzed reactions are employed as the key steps in the synthesis of three phenolic natural products: Plicatin B, Drupanin and Eutypine.