FORMAL SYNTHESIS OF (+ -)-AMBROX(R)

Authors
BARCO A BENETTI S BIANCHI A CASOLARI A GUARNERI M POLLINI GP
Citation
A. Barco et al., FORMAL SYNTHESIS OF (+ -)-AMBROX(R), Tetrahedron, 51(30), 1995, pp. 8333-8338
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
51
Issue
30
Year of publication
1995
Pages
8333 - 8338
Database
ISI
SICI code
0040-4020(1995)51:30<8333:FSO(->2.0.ZU;2-#
Abstract
The immediate precursor of (+/-)-Ambrox(R) has been conveniently prepa red in a seven-step sequence starting from the readily available methy l 2-oxo-5,5,8a-trimethyldecahydronaphthalene 1-carboxylate 2, in turn derived by stannic chloride-mediated cyclization of methyl 3-oxo-5(2,6 ,6-trimethylcyclohexen-1-yl)pentanoate.