Purpose: To report the immediate and long-term outcome of intraoperati
ve balloon angioplasty for the treatment of recurrent disease in the i
nternal carotid arteries (ICAs). Methods: Three patients (2 males, 1 f
emale; ages 53 to 70 years) presented with > 80% restenotic lesions (b
ilateral in one patient) at the distal aspect of a previous carotid en
darterectomy. Two patients exhibited hemianopia, while the third was a
symptomatic but had a contralateral ICA occlusion. All four lesions ap
peared smooth and fibrous on ultrasonography and were located high in
the ICA. The location and morphology of the lesions made balloon angio
plasty a more potentially successful treatment option. Results: Throug
h open access to the common carotid artery, the lesions were approache
d and dilated under fluoroscopic guidance with monitoring of evoked po
tentials. The lesions were successfully dilated as determined by contr
ol arteriography, and no complications were encountered. Over a follow
-up period extending to 18 months in one patient and 24 months in the
other two, ultrasound imaging and arteriography have shown no restenos
is at any treatment site. Conclusions: Although caution is prudent whe
n dealing with lesions in the cervical arteries, balloon angioplasty m
ay have a role in treating surgically inaccessible restenotic carotid
lesions that demonstrate a low potential for embolic complications. Mo
re experience with this technique will be required before widespread a
pplication of balloon angioplasty in the cervical vessels can occur.