K. Sondenaa et Ml. Pollard, HISTOLOGY OF CHRONIC PILONIDAL-SINUS, APMIS. Acta pathologica, microbiologica et immunologica Scandinavica, 103(4), 1995, pp. 267-272
Many theories concerning the development of chronic pilonidal sinus ha
ve been proposed. A histologic study of primary pilonidal sinus in 53
patients is presented. Subcutaneous tissue contained sinuses surrounde
d by chronic inflammation. Hair in sinuses was found in three quarters
of the specimens examined. Examination showed that hair entered via o
ne of the sinus openings created. Pits (defined as darker spots of var
ying width in the midline of the internatal cleft) were found to be in
dentations of the skin containing keratin plugs and debris. They may b
e isolated or connected with hair follicles. Pilonidal sinuses are chr
onic inflammatory processes of the skin caused by keratin plugs and de
bris clinically observed as pits, having penetrated the dermis.