SYNTHESIS OF DIPHOSPHATE AND TRIPHOSPHATE ESTER ANALOGS VIA A MODIFIED MICHAELIS-ARBUZOV REACTION

Authors
SAADY M LEBEAU L MIOSKOWSKI C
Citation
M. Saady et al., SYNTHESIS OF DIPHOSPHATE AND TRIPHOSPHATE ESTER ANALOGS VIA A MODIFIED MICHAELIS-ARBUZOV REACTION, Tetrahedron letters, 36(29), 1995, pp. 5183-5186
Citations number
34
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
29
Year of publication
1995
Pages
5183 - 5186
Database
ISI
SICI code
0040-4039(1995)36:29<5183:SODATE>2.0.ZU;2-9
Abstract
For the first time, benzyl phosphites allowed the preparation of a set of polyphosphonates from chloromethyl halides via the Michaelis-Arbuz ov reaction performed under vacuum. Regioselective mono-deprotection o r complete deprotection of these phosphonates provide useful building blocks for the synthesis of biological phosphate analogs.