SIMPLE TOTAL SYNTHESES OF N-SUBSTITUTED POLYAMINE DERIVATIVES USING N-TRITYLAMINO ACIDS

Authors
MAMOS P KARIGIANNIS G ATHANASSOPOULOS C BICHTA S KALPAXIS D PAPAIOANNOU D SINDONA G
Citation
P. Mamos et al., SIMPLE TOTAL SYNTHESES OF N-SUBSTITUTED POLYAMINE DERIVATIVES USING N-TRITYLAMINO ACIDS, Tetrahedron letters, 36(29), 1995, pp. 5187-5190
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
29
Year of publication
1995
Pages
5187 - 5190
Database
ISI
SICI code
0040-4039(1995)36:29<5187:STSONP>2.0.ZU;2-H
Abstract
A general methodology for the total synthesis of N-alkyl- and acylpoly amine derivatives is described which is based on the coupling of suita ble N-tritylamino acids with amines followed by lithium aluminium hydr ide reduction of the thus obtained amides.