SYNTHESIS OF BRACKEN ULTIMATE CARCINOGEN ANALOGS POSSESSING A DNA-BINDING MOIETY AND THEIR DNA-CLEAVING ACTIVITIES

Authors
KIGOSHI H NIWA M OHASHI H TANAKA H HIROKAWA J ISHIWATA H YAMADA K
Citation
H. Kigoshi et al., SYNTHESIS OF BRACKEN ULTIMATE CARCINOGEN ANALOGS POSSESSING A DNA-BINDING MOIETY AND THEIR DNA-CLEAVING ACTIVITIES, Tetrahedron letters, 36(30), 1995, pp. 5349-5352
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
30
Year of publication
1995
Pages
5349 - 5352
Database
ISI
SICI code
0040-4039(1995)36:30<5349:SOBUCA>2.0.ZU;2-A
Abstract
Two bracken ultimate carcinogen analogues possessing a DNA binding moi ety, 4 and 5, have been synthesized and have been found to cleave DNA more effectively than the control compounds, 21 and 22, that have no D NA binding moiety.