PHOTOGENERATION OF HIGHLY ELECTROPHILIC BENZOYLKETENE FROM DIBENZOYLDIAZOMETHANE IN AQUEOUS SOLVENTS - REACTION WITH AMINO-ACIDS AND DNA CLEAVAGE

Authors
NAKATANI K SHIRAI J TAMAKI R SAITO I
Citation
K. Nakatani et al., PHOTOGENERATION OF HIGHLY ELECTROPHILIC BENZOYLKETENE FROM DIBENZOYLDIAZOMETHANE IN AQUEOUS SOLVENTS - REACTION WITH AMINO-ACIDS AND DNA CLEAVAGE, Tetrahedron letters, 36(30), 1995, pp. 5363-5366
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
30
Year of publication
1995
Pages
5363 - 5366
Database
ISI
SICI code
0040-4039(1995)36:30<5363:POHEBF>2.0.ZU;2-4
Abstract
Photoirradiation of dibenzoyldiazomethane in the presence of amino aci d derivatives in aqueous solutions efficiently produced the addition p roducts through a reaction with photogenerated benzoylketene. Efficien t DNA cleavage was observed with a dibenzoyldiazomethane derivative, p ossessing a cationic side chain under photoirradiation conditions.