ANTIBIOTIC-RESISTANCE OF VIBRIO-ANGUILLARUM, IN RELATION TO SEROVAR AND PLASMID CONTENTS

A total of 520 Vibrio anguillarum strains, isolated from fish and the environment, were tested for their sensitivity to 20 different antibio tics. Most isolates were of European origin. The results were compared with data on the O-serogroup and plasmid contents. All strains were s ensitive to neomycin, spectinomycin, nitrofurantoin, flumequine and ox olinic acid, while most strains were sensitive to streptomycin, oxytet racycline, chloramphenicol, sulphonamides, trimethoprim, sulphonamides with trimethoprim, nalidixan, rifampicin, novobiocin and O/129. A maj or part of the strains were resistant to the macrolides, spiramycin an d lincomycin. For ampicillin, cephalothin, and colistin marked differe nces were recorded with respect to O-serogroup. Most O1 strains were r esistant to colistin and sensitive to ampicillin and cephalothin, whil e most O2 strains were sensitive to colistin but resistant to ampicill in and cephalothin. Some antibiotic resistant strains carried plasmids but no conjugation experiments were carried out to detect possible R factors.