ON THE MECHANISM OF BAKERS YEAST-MEDIATED SYNTHESIS OF S-BENZYL (R)-THIOGLYCERATE - EXPERIMENTS WITH C-3 PRECURSORS

Authors
FRONZA G FUGANTI C MELE A PEDROCCHIFANTONI G SARRA A SERVI S
Citation
G. Fronza et al., ON THE MECHANISM OF BAKERS YEAST-MEDIATED SYNTHESIS OF S-BENZYL (R)-THIOGLYCERATE - EXPERIMENTS WITH C-3 PRECURSORS, Gazzetta chimica italiana, 125(7), 1995, pp. 305-308
Citations number
11
Categorie Soggetti
Chemistry
Journal title
Gazzetta chimica italiana → ACNP
ISSN journal
00165603
Volume
125
Issue
7
Year of publication
1995
Pages
305 - 308
Database
ISI
SICI code
0016-5603(1995)125:7<305:OTMOBY>2.0.ZU;2-7
Abstract
Deuterium labelling experiments with baker's yeast in the presence of dihydroxyacetone (DHA) and benzyl mercaptan allow the preparation of e nantiomerically pure glycerol analogues, with different extents of lab el in different position. The mode of the enzymatic conversion of 3 in to 1 is supported by H-2 NMR studies onto the biotransformation produc ts 9.