CHROMOSOMES TAKE THE LEAD IN SPINDLE ASSEMBLY

Authors
VERNOS I KARSENTI E
Citation
I. Vernos et E. Karsenti, CHROMOSOMES TAKE THE LEAD IN SPINDLE ASSEMBLY, Trends in cell biology, 5(8), 1995, pp. 297-301
Citations number
20
Categorie Soggetti
Cell Biology
Journal title
Trends in cell biology → ACNP
ISSN journal
09628924
Volume
5
Issue
8
Year of publication
1995
Pages
297 - 301
Database
ISI
SICI code
0962-8924(1995)5:8<297:CTTLIS>2.0.ZU;2-A
Abstract
Several kinesin-like motor proteins have recently been found associate d with chromosome arms. They seem to be involved in the so-called 'pol ar ejection forces' that contribute to the congression of chromosomes on the metaphase plate, and at least one of them is essential for the maintenance of spindle bipolarity. The discovery of these molecules ch anges our view of the mechanism of spindle assembly and chromosome mov ement.