CONTROL OF THERAPEUTIC REMISSION IN ALCOH OLIC PATIENTS

Usage of alcohol during the period of therapeutic remission of chronic alcoholism without complete restoration of its symptoms indicates fai lure of therapeutic remission (FTR). A method was suggested to detect FTR by enzymic activity of gamma-glytamyltranspeptidase, aspartate tra nsaminase, alanintransaminase and glutamate dehydrogenase. FTR is stat ed at differiential threshold of the above enzymes 32, 25, 26 and 6,5 u/l, respectively. Validity of the method was confirmed at examination of 110 chronic alcoholics and 61 healthy persons. Early FTR detection prevents occurrence of true recurrence of chronic alcoholism.