BENDAZAC HEPATOTOXICITY - ANALYSIS OF 16 CASES

Hepatic lesions induced by non-steroid anti-inflammatory drugs are a c ommon cause of disease, particularly among elderly patients. Although its clinical expression is polymorphous, occasional increases in serum transaminase values predominate, Sixteen cases of liver involvement b y bendazac were studied. This NSAID is used in Spain for the treatment of cataracts, from a total of 112 patients observing such therapy. Th e clinical spectrum of liver disease induced by bendazac is discussed and emphasis is placed on the necessity to judiciously select the indi cations for NSAIDs.