Ultrasonic energy has not been previously used for surgical cutting an
d coagulating. Work in our laboratory has led to the development of an
ultrasonically activated scalpel that safely and effectively cuts and
coagulates tissue in animals. The purpose of this study was to determ
ine if ultrasonic energy can replace monopolar electrosurgery in human
laparoscopic surgery. Two hundred consecutive patients underwent lapa
roscopic cholecystectomy with the ultrasonically activated scalpel. Th
e scalpel was the sole energy form in 98 of the first 100 patients, an
d in all of the last 100 patients. There were no common duct injuries,
reoperations, or mortality. No patient had more than a 3-g drop in he
moglobin or transfusion. The ultrasonically activated scalpel is a saf
e and effective energy form for cutting and coagulating tissue during
laparoscopic cholecystectomy in humans. The absence of need of monopol
ar electrosurgery combined with hemostatic effectiveness supports the
concept that the ultrasonically activated scalpel can replace electros
urgery for laparoscopic cholecystectomy.