A RETROSPECTIVE ANALYSIS OF TWICE-DAILY CEFOTAXIME COMPARED TO CONVENTIONAL THERAPY FOR THE TREATMENT OF INFECTIONS IN A USA HOSPITAL

Authors
BURKE JP PESTOTNIK SL CLASSEN DC LLOYD JF
Citation
Jp. Burke et al., A RETROSPECTIVE ANALYSIS OF TWICE-DAILY CEFOTAXIME COMPARED TO CONVENTIONAL THERAPY FOR THE TREATMENT OF INFECTIONS IN A USA HOSPITAL, Diagnostic microbiology and infectious disease, 22(1-2), 1995, pp. 167-169
Citations number
8
Categorie Soggetti
Microbiology,"Infectious Diseases
Journal title
Diagnostic microbiology and infectious disease → ACNP
ISSN journal
07328893
Volume
22
Issue
1-2
Year of publication
1995
Pages
167 - 169
Database
ISI
SICI code
0732-8893(1995)22:1-2<167:ARAOTC>2.0.ZU;2-J
Abstract
A retrospective, matched cohort study was performed to determine the c ost outcomes among 495 hospitalized patients who received twice-daily dosing of cefotaxime and 3949 matched cohorts who received other antib iotics. By an attribution model, twice-daily use was associated with s horter mean lengths of stay (-0.498 day, P <.7) and lower mean total c osts of hospitalization (-$623, P <.8). Twice-daily dosing of cefotaxi me is commonly employed for the treatment of a variety of serious infe ctions, and appears to be cost effective.