Detailed medical and clinical examinations were carried out an 1608 me
n attending an infertility clinic to determine if any of those exhibit
ing abnormal semenograms also had any other readily identifiable clini
cal condition. In all, 1210 men showed abnormal semenograms according
to World Health Organization criteria. Karyotyping of the white blood
cells in these 1210 men revealed 44 (3.6%) individuals with either aut
osomal or sex chromosomal aberrations, However, no single characterist
ic feature of their semenogram or clinical condition was of any diagno
stic value to predict the existence of a chromosomal anomaly.