During a 12 month period, tissue was collected from 30 surgically mana
ged patients presenting with vital ectopic pregnancies, Chorionic vill
i of the removed tissue were successfully karyotyped by (semi-) direct
chromosome technique in 22 cases. Only one abnormal chromosomal compl
ement, a triploidy (69,XXX) was found, As controls, 10 cases of intrau
terine pregnancies were investigated, all showing a normal karyotype,
These findings do not suggest an important role for chromosome abnorma
lities in the aetiology of vital ectopic pregnancies.