STREPTOCOCCAL TOXIC SHOCK SYNDROME - REPORT OF 2 CASES

Two Japanese cases of streptococcal toxic shock syndrome (STSS) are re ported, The first patient was a 45-year-old male who developed necroti zing fasciitis and myositis of the left thigh, refractory hypotension, hepatic dysfunction and acute renal failure; the patient died despite treatment, Streptococcus pyogenes was isolated from the inflamed fasc ia, The second patient was a 69-year-old female who had coagulopathy, polymyositis and hepatic function abnormality, Streptococcus pyogenes was isolated from blood culture. She was immediately placed on high-do se ampicillin as well as other supportive measures, and she survived.