SYNTHESIS AND STEREOSTRUCTURE OF SOME RO[MORPHINAN-6,2'(3'H)-[1,3,4]OXA(THIA)DIAZOLINES]

Authors
SOMOGYI L SZABO Z HOSZTAFI S
Citation
L. Somogyi et al., SYNTHESIS AND STEREOSTRUCTURE OF SOME RO[MORPHINAN-6,2'(3'H)-[1,3,4]OXA(THIA)DIAZOLINES], Liebigs Annalen, (7), 1995, pp. 1393-1395
Citations number
13
Categorie Soggetti
Chemistry
Journal title
Liebigs Annalen → ACNP
ISSN journal
09473440
Issue
7
Year of publication
1995
Pages
1393 - 1395
Database
ISI
SICI code
0947-3440(1995):7<1393:SASOSR>2.0.ZU;2-I
Abstract
Treatment of dihydrocodenione (thio)semicarbazones 1a-d with Ac2O/ZnCl 2 afforded S)-spiro[morphinan-6,2'(3'H)-[1,3,4]oxadiazolines] (2a, b) and )-spiro[morphinan-6,2'(3'H)-[1,3,4]thiadiazolines] (3a, b), respec tively. The structure of the products including the configuration of t he spiro carbons was determined by H-1- and C-13-NMR measurements.