Isocenter calibration transforms cardiac structures in digitized bipla
ne angiograms to absolute dimensions, calculating their radiological m
agnification and video transformation. Since a scaling device is not r
equired, isocenter calibration yields to more accurate measurements th
an the widely used reference object calibration. Both isocenter method
s reported so far, regarding geometrically inaccurate x-ray gantries,
yield to different and complex computational formulas. Since these for
mulas are hard to understand, isocenter calibration is less widely use
d. To facilitate the implementation of the isocenter calibration, the
basic formulas for accurate x-ray gantries are derived. Shifting virtu
ally one x-ray system onto the other, basic isocenter calibration is d
erived geometrically in three simple steps. The radiological magnifica
tion of an object is illustrated as a ratio of planes. The calculation
of all parameters entering the computations is demonstrated geometric
ally, by use of the isocenter of the x-ray gantry. The derivation give
s a clear idea of isocenter calibration. It is simple to derive and fa
cilitates the understanding of the error regarding developments. When
geometrical inaccuracies vanish, all formulas become equivalent. Howev
er, even if the inaccuracies increase, all methods provide nearly iden
tical results, indicating the robustness of isocenter calibration.