MODIFICATION OF ALBUMINS BY GRAFTING POLY(AMIDO AMINE) CHAINS

Authors
RANUCCI E BIGNOTTI F PADERNO PL FERRUTI P
Citation
E. Ranucci et al., MODIFICATION OF ALBUMINS BY GRAFTING POLY(AMIDO AMINE) CHAINS, Polymer, 36(15), 1995, pp. 2989-2994
Citations number
23
Categorie Soggetti
Polymer Sciences
Journal title
Polymer → ACNP
ISSN journal
00323861
Volume
36
Issue
15
Year of publication
1995
Pages
2989 - 2994
Database
ISI
SICI code
0032-3861(1995)36:15<2989:MOABGP>2.0.ZU;2-T
Abstract
Bovine serum albumin and human serum albumin have been modified by gra fting poly(amido amine) chains via a hydrogen-transfer addition reacti on involving the available amino groups of the protein, in which the a minic character of the latter is preserved. The chemical processes inv olved are probably of general application for grafting multifunctional polymeric chains on to proteins under very mild, non-denaturing condi tions.