Aim: To find a useful measure of the severity of subjective distress f
or patients with personality disorders. The measure should be minimall
y confounded by coexisting anxiety and mood disorders. Material: Forty
-seven patients with schizotypal and/or borderline personality disorde
rs were compared to 41 patients with Cluster C personality disorders a
nd Axis I disorders only. Methods: Diagnoses were reliably assessed ac
cording to Diagnostic and Statistical Manual of Mental Disorders (DSM-
III-R) criteria. The self-report inventory SCL-90-R was administered i
n a state of decompensation, after day hospital treatment and at 3 yea
r follow-up. Results: Borderline and schizotypal patients perceived th
emselves as more interpersonally vulnerable and more aggressive, and p
erceived others as more hostile at all three points in time. We sugges
t personality severity index (PSI) as a label for the mean score of th
e SCL-90-R subscales interpersonal sensitivity, hostility, and paranoi
d ideation. This index differentiated between schizotypal/borderline a
nd Cluster C/Axis I disorders even when statistically corrected for th
e influence of anxiety and mood disorders. The PSI was more stable ove
r time than the other SCL-90-R symptom subscales, in particular compar
ed with anxiety and depression subscales. Conclusion: The PSI might be
a useful measure of the severity of subjective distress for patients
with Cluster A and B personality disorders.