As a chronic disease with intermittent exacerbations, asthma is treate
d primarily in the outpatient setting by primary care physicians. Asth
ma is the result of complex and only partially understood interactions
of respiratory inflammatory, and neural cells and their mediators. Th
e goals of asthma therapy are to prevent and relieve symptoms, allow n
ormal activities of daily living, restore and maintain normal pulmonar
y function, avoid adverse effects from interventions, and minimize inc
onvenience and cost. These goals can be achieved through educating pat
ients, assessing and monitoring asthma severity, avoiding or controlli
ng asthma triggers, establishing an intervention plan for routine self
-management and the management of exacerbations, and providing regular
follow-up care. We present a stepped approach to asthma pharmacothera
py, emphasizing anti-inflammatory therapy-inhaled corticosteroids, cro
molyn sodium, or nedocromil sodium-as a summary of recent national and
international recommendations.