INVASIVE GERM-CELL TUMOR-DETECTED BY FOLLOW-UP EXAMINATION FOLLOWING ORCHIOPEXY FOR CRYPTORCHIDISM

The authors report the case of a 26-year-old man who was operated upon for bilateral testicular maldescent when he was 11 years old. In a fo llow-up examination for men with a history of orchiopexy for cryptorch idism, he palpated a dense nodule emerging from his right testis, and therapy for invasive testicular cancer was started. The histologic dia gnosis was a mixed teratoma consisting of yolk-sac tumor, differentiat ed teratoma, and embryonic carcinoma. We conclude that young men with a history of testicular maldescent should be followed up by a multidis ciplinary approach and should be offered testicular biopsy after puber ty to allow detection and treatment of testicular intraepithelial neop lasia (so-called testicular carcinoma in situ) to prevent invasive tes ticular cancer.