CUTANEOUS ANGIOMYXOMA - A BENIGN NEOPLASM DISTINCT FROM CUTANEOUS FOCAL MUCINOSIS

We describe a cutaneous angiomyxoma on the head of a 38-year-old man w ithout evidence of Carney's complex. Complete excision of the tumor ap peared to be curative. Histologic examination revealed fibroblast-like cells embedded in a well-demarcated, lobulate, mucinous, and vascular ized stroma with a delicate reticulin network. Immunohistologically, t he stromal cells were consistently positive for vimentin and focally p ositive for smooth muscle A-actin but were negative for desmin, KP1, M AC387, factor XIIIa, CD34, Leu-7, and S-100. Cutaneous angiomyxoma app ears to represent a myofibroblastic neoplasm that should be distinguis hed from cutaneous focal mucinosis.