M. Sano et al., EFFECT OF TEA (CAMELLIA-SINENSIS L) ON LIPID-PEROXIDATION IN RAT-LIVER AND KIDNEY - A COMPARISON OF GREEN AND BLACK TEA FEEDING, Biological & pharmaceutical bulletin, 18(7), 1995, pp. 1006-1008
The antioxidant effects in the liver and kidney obtained from rats fed
diets containing 3% green or black tea leaf powder, which were prepar
ed from the same lot tea leaves, were studied using the tissue slice-a
ntioxidant evaluation method with two lipid peroxidation inducers. Aft
er 50 d on the diets, liver slices prepared from green and black tea-s
upplemented rats showed significant inhibitory effects against tert-bu
tyl hydroperoxide-induced lipid peroxidation. These effects, however,
were not proportional to the amounts of (-)-epicatechins and antioxida
nt vitamins in the tea leaves. In the kidney, the antioxidant effect w
as observed only in the green tea-fed group. A similar antioxidant eff
ect on the kidney was observed after oral administration of a major te
a polyphenol, (-)-epigallocatechin gallate (50mg/kg body weight for 7
d). Liver slices from black tea-fed rats also inhibited bromotrichloro
methane-induced lipid peroxidation. These results demonstrated that di
etary green and black tea had antioxidant effects on tissue lipid pero
xidation ex vivo.