AIRWAY REMODELING IN ASTHMA

There is a wealth of evidence in favour of the existence of bronchial remodelling in asthma. This repair process involves structural and inf lammatory cells as well as extracellular matrix. All these structures are present and activated in the bronchi of asthmatic patients. These phenomena may have clinical consequences, but they have not been direc tly demonstrated. The action of antiasthmatic treatments, especially c orticosteroids, requires further evaluation by long-term prospectives studies.