FACILE SYNTHESIS OF YL-3,4-DIMETBOXY-6-TRIMETHYL-STANNYLPHENETHYLAMINE - A CONVENIENT PRECURSOR TO 6-[F-18]FLUORODOPAMINE

Authors
CULBERT PA ADAM MJ JIVAN S
Citation
Pa. Culbert et al., FACILE SYNTHESIS OF YL-3,4-DIMETBOXY-6-TRIMETHYL-STANNYLPHENETHYLAMINE - A CONVENIENT PRECURSOR TO 6-[F-18]FLUORODOPAMINE, Applied radiation and isotopes, 46(9), 1995, pp. 883-885
Citations number
9
Categorie Soggetti
Nuclear Sciences & Tecnology","Radiology,Nuclear Medicine & Medical Imaging
Journal title
Applied radiation and isotopes
ISSN journal
09698043 → ACNP
Volume
46
Issue
9
Year of publication
1995
Pages
883 - 885
Database
ISI
SICI code
0969-8043(1995)46:9<883:FSOY>2.0.ZU;2-Y
Abstract
A convenient three-step synthesis of the title compound from commercia lly available 3,4-dimethoxyphenethylamine is described. The title comp ound is a stable, crystalline, organic-soluble solid which reacts with carrier-added [F-18]acetyl hypofluorite to yield 6-[F-18]fluorodopami ne (20 +/- 7% radiochemical yield EOS, n = 3) following deprotection w ith hydriodic acid.