Citation
Pa. Culbert et al., AUTOMATED SYNTHESIS OF [F-18] FDG USING TETRABUTYLAMMONIUM BICARBONATE, Applied radiation and isotopes, 46(9), 1995, pp. 887-891
Citations number
6
Categorie Soggetti
Nuclear Sciences & Tecnology","Radiology,Nuclear Medicine & Medical Imaging
Journal title
Applied radiation and isotopes
ISSN journal
09698043
→ ACNP
Volume
46
Issue
9
Year of publication
1995
Pages
887 - 891
Database
ISI
SICI code
0969-8043(1995)46:9<887:ASO[FU>2.0.ZU;2-W
Abstract
The synthesis of [F-18]FDG using tetrabutylammonium bicarbonate has be
en successfully modified to accommodate automation using the Optomux(R
) control system. Noteworthy changes to the methods previously reporte
d are the addition of a small ion exchange column which serves to quan
titatively trap [F-18]fluoride from the target water and the extensive
use of thermocouple and radiation detector feedback for process contr
ol. The radiochemical yields observed over 30 runs are: 50.3 +/- 9% de
cay corrected and 34.6 +/- 6% decay uncorrected.