Foot disease in patients with diabetes mellitus is multifactorial and
results from a combination of peripheral neuropathy, vascular compromi
se and superimposed infection. Foot complications in diabetic patients
are common and account for more hospital days than any other aspects
of their disease. Therefore, familiarity with the spectrum of findings
in the different imaging modalities appears essential. Radiographical
ly, significant changes include Charcot joints of the tarsus (destruct
ive type) and bone absorption of the forefoot (mutilating type). In di
abetic foot problems, magnetic resonance imaging and leukocyte scintig
raphy appear to be the most effective tools for detection of osteomyel
itis, and a negative study makes osteomyelitis unlikely. However, the
findings of both techniques in active, noninfected neuropathic osteoar
thropathy may be indistinguishable from those of osteomyelitis.