Objective: This study examined the correlation between the worst abbre
viated injury scale 1990 (AIS) intracranial severity score and outcome
following severe head injury. Design: The initial CT scans of 109 sev
erely head injury patients were examined by a neuroradiologist and cla
ssified according to the worst applicable intracranial severity code f
rom the AIS. This score was then correlated with the glasgow outcome s
cale (GOS) at 6 months. For comparison, the GOS was also correlated wi
th the diffuse injury scale (DIS) described by L.F. Marshall et al. [5
], the worst post-resuscitation Glasgow coma score (GCS) in the first
24 h, and the head injury outcome prediction tree described by Choi et
al. [1]. Results: Our results show Spearman rank correlation coeffici
ents of 0.58 (p < 0.001), 0.47 (p < 0.001), 0.45 (p < 0.001), and 0.31
(p < 0.01) for the correlation between the AIS, prediction tree, DIS,
and GCS respectively and the GOS. Independent outcome (i.e. GOS good
or moderate) was strongly predicted by an AIS of 3 or less (positive p
redictive value 95%, specificity 98%, sensitivity 40%, likelihood rati
o 25:1). Death or vegetative survival was less strongly predicted in p
atients with an AIS of 5 (positive predictive value 71%, specificity 7
5%, sensitivity 67%, likelihood ratio 2.7:1). Conclusion: The AIS, bas
ed on initial CT scan, provides useful prognostic information in patie
nts with severe head injury.