T. Ingebrigtsen et al., MANAGEMENT OF MINOR HEAD-INJURY - THE VALUE OF EARLY COMPUTED-TOMOGRAPHY AND SERUM-PROTEIN S-100 MEASUREMENTS, Journal of clinical neuroscience, 4(1), 1997, pp. 29-33
Computed tomography (CT) scan was performed within 6 h in 91 patients
with minor head injury (MHI). Eight patients (9%) demonstrated intracr
anial lesions on CT scan (6 brain contusions, 1 brain edema and 1 extr
adural hematoma), No patient required craniotomy, In patients with nor
mal CT scan, no complications to the head injury were observed, Patien
ts with intracranial lesions were hospitalized significantly longer (m
ean 9.4 days) than patients without (mean 1.6 days), In a subgroup of
50 patients with normal CT scan, serum S-100 protein was measured on a
dmission, Elevated S-100 levels were seen in 10 of 50 patients (0.5-2.
4 mu g/L, mean 1.1), These patients were hospitalized significantly lo
nger (mean 3.4 days) compared to patients with normal CT scan and norm
al S-100 levels (mean 1.1 days), MHI patients with GCS 14-15 without n
eurological deficits can safely be discharged when CT scan is normal,
Serum protein S-100 measurements appear to provide information about d
iffuse brain injury after MHI. (C) Pearson Professional Ltd 1997