A BIOACTIVE TETRAPRENYLPHENOL FROM LACTARIUS-LIGNYOTUS

Authors
VIDARI G VITAFINZI P ZANOCCHI AM NOY GP
Citation
G. Vidari et al., A BIOACTIVE TETRAPRENYLPHENOL FROM LACTARIUS-LIGNYOTUS, Journal of natural products, 58(6), 1995, pp. 893-896
Citations number
19
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
58
Issue
6
Year of publication
1995
Pages
893 - 896
Database
ISI
SICI code
0163-3864(1995)58:6<893:ABTFL>2.0.ZU;2-P
Abstract
2-Geranylgeranyl-1,4-dihydroxybenzene [1] and a mixture of fatty acid esters of this phenol were isolated from the fruiting bodies of Lactar ius lignyotus. Compound 1 was highly active in the brine shrimp test a nd showed significant inhibitory activity on DNA, RNA, and protein syn thesis in HeLa and HL-60 cell lines.