EXPERIMENTAL-STUDY OF PHYSIOLOGICAL ADVANTAGES OF ASSIST CIRCULATION USING OSCILLATED BLOOD-FLOW

To estimate the effect of oscillated blood flow on hemodynamics in an awake condition, left ventricular assist circulation using oscillated blood flow was performed on 3 adult goats as chronic animal examinatio n. A vibrating flow pump (VFP) was used for generating high-frequency oscillated flow. The blood flow rate of assisted circulation was appro ximately 1.0 L/min, and the driving frequency of VFP was 25 Hz. System ic vascular resistance and arterial impedance were calculated in this study. Systemic vascular resistance during assist circulation was decr eased compared with that without assistance. Oscillated blood flow may be effective in decreasing vascular resistance. Moreover, it was sugg ested from the study of arterial impedance that motive characteristics of the vascular wall against changing blood pressure may keep their n ormal reaction. Therefore, oscillated blood flow may be used for left ventricular assist circulation as concluded from the study of the char acteristics of blood vessels.