E. Senneville et al., PREVALENCE OF SUBCLINICAL SINUS DISEASE I N HIV-POSITIVE PATIENTS EVALUATED BY COMPUTED-TOMOGRAPHY VERSUS A CONTROL POPULATION, La Semaine des hopitaux de Paris, 73(1-2), 1997, pp. 7-12
To determine the prevalence of subclinical sinus disease in patients i
nfected with the human immunodeficiency virus (HIV), cerebral computed
tomography scans (CCT) done at the Tourcoing hospital over an 18-mont
h period in 139 HIV-positive patients and 140 control patients without
evidence of active sinus disease were reviewed retrospectively. CCTs
were evaluated independently by two physicians who were blinded to cli
nical data. Mucosal thickening and/or a full sinus were more common in
HIV-positive patients (20/139, 14.4%) than in the controls (8/140, 5.
7%) (p=0.016). Mucosal thickening was the most common abnormality in b
oth groups, CD4+ cell counts were not correlated with the radiographic
abnormalities studied. These radiographic data suggest that subclinic
al chronic sinusitis Independent from the degree of immune deficiency
may be more common in HIV-positive than in HIV-negative subjects.