BACKBONE MODIFICATION OF CHIRASIL-VAL - EFFECT OF NONPOLAR SIDE-CHAINS ON ENANTIOMER SEPARATION IN GAS-CHROMATOGRAPHY

Authors
KOPPENHOEFER B MUHLECK U LOHMILLER K
Citation
B. Koppenhoefer et al., BACKBONE MODIFICATION OF CHIRASIL-VAL - EFFECT OF NONPOLAR SIDE-CHAINS ON ENANTIOMER SEPARATION IN GAS-CHROMATOGRAPHY, Chromatographia, 40(11-12), 1995, pp. 718-723
Citations number
29
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Journal title
Chromatographia → ACNP
ISSN journal
00095893
Volume
40
Issue
11-12
Year of publication
1995
Pages
718 - 723
Database
ISI
SICI code
0009-5893(1995)40:11-12<718:BMOC-E>2.0.ZU;2-D
Abstract
The polysiloxane backbone of the gas chromatography phase Chirasil-Val has been modified by replacing one methyl group per dialkylsiloxy uni t by pentyl and hexyl groups, respectively. The new phases offer the a dvantage of reduced polarities and softening points, while the separat ion factors (alpha) of enantiomeric pairs of N,O-trifluoroacetyl amino acid propyl esters show small but intriguing deviations from those de termined on Chirasil-Val.