EVALUATION OF MAGNETIC-RESONANCE-IMAGING FOR QUANTIFICATION OF INTRAABDOMINAL FAT IN HUMAN-BEINGS BY SPIN-ECHO AND INVERSION-RECOVERY PROTOCOLS

We evaluated two magnetic resonance imaging (MRI) methods, spin echo a nd inversion recovery (IR), for quantification of intraabdominal fat i n a subgroup of participants from the Atherosclerosis Risk in Communit ies (ARIC) Study. Both methods were used previously to quantify viscer al fat, and the IR but not the spin echo method has been validated by comparison with computed tomography in human beings. In the present st udy, the reliability of both methods was excellent: reliability coeffi cients comparing two readers on the same scan were 0.9574 for IR (n = 158) and 0.9254 for spin echo (n = 47) when random effects models with log-transformed data were used. A comparison of visceral fat areas in 47 subjects with both IR and spin echo indicated that IR gave a sligh tly higher mean area than did spin echo: 134.9 compared with 129.8 cm( 2). However, a mixed-model analysis of variance (ANOVA) of the log-tra nsformed data showed no statistical difference between either method o r readers in the comparison of IR and spin echo. These data suggest th at the IR and spin echo protocols evaluated in this communication are comparable with one another and reliable for estimation of intraabdomi nal fat.