EXACERBATION OF HAILEY-HAILEY DISEASE BY HERPES-SIMPLEX VIRUS - DIAGNOSIS BY POLYMERASE CHAIN-REACTION

Authors
SCHIRREN H SCHIRREN CG SCHLUPEN EM VOLKENANDT M KIND P
Citation
H. Schirren et al., EXACERBATION OF HAILEY-HAILEY DISEASE BY HERPES-SIMPLEX VIRUS - DIAGNOSIS BY POLYMERASE CHAIN-REACTION, Hautarzt, 46(7), 1995, pp. 494-497
Citations number
22
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
Hautarzt → ACNP
ISSN journal
00178470
Volume
46
Issue
7
Year of publication
1995
Pages
494 - 497
Database
ISI
SICI code
0017-8470(1995)46:7<494:EOHDBH>2.0.ZU;2-B
Abstract
A 49-year-old man suffered from Hailey-Hailey disease for several year s. The patient presented with an acute exacerbation of the disease, wh ich did not respond to oral treatment with high doses of glucocorticos teroids. A skin biopsy was taken and the histological examination indi cated a viral infection. Herpes simplex virus was confirmed by electro n microscopy (negative staining) and polymerase chain reaction (PCR). The PCR presents a sensitive and effective molecular-biological method for the diagnosis of viral infections.