PARAKERATOSIS VARIEGATA FOLLOWING PITYRIA SIS LICHENOIDES ET VARIOLIFORMIS ACUTA

We report on a 34-year-old male patient who developed generalized para keratosis variegata lesions 4 years after suffering from pityriasis li chenoides et varioliformis acuta. For further investigation of a possi ble interrelationship between these two diseases of the parapsoriasis group and their relationship to the T-celI type of cutaneous non-Hodgk in-lymphoma, histological, immunohistological and molecularbiological techniques were applied. We were able to demonstrate typical morpholog ical features common to both diseases, and a polyclonal T-cell infiltr ate in both. It is concluded that pityriasis lichenoides et variolifor mis acuta and parakeratosis variegata are separate entities without mo noclonal rearrangement or signs of malignancy.