GRANULOCYTIC SARCOMAS - CLINICAL, DIAGNOSTIC AND THERAPEUTIC ASPECTS

Granulocytic sarcomas (GS) are extramedullary tumor masses of immature myeloid cells most frequently associated with acute myeloblastic leuk emia. We report our diagnostic, clinic and therapeutic approaches in t he treatment of 6 patients affected by GS who presented with different localizations and symptoms: mediastinal mass with chest pain, rectal tumor with bowel occlusion, bladder mass with acute kidney failure, qu adriceps tumor with pain, vertebral localization with pain and bowel m ass with pain, respectively. The correct diagnosis of CS by bone biops y, the immunohistological evaluation of the tumor masses, the prompt u se of active drugs in the first line therapy schedule as for acute mye loblastic leukemia are the parameters for the achievement of the long- term remission.