EFFECT OF HEPARIN ON HEMAGGLUTINATION BY AKABANE AND AINO VIRUSES BELONGING TO THE SIMBU GROUP OF BUNYAVIRUSES

Authors
JUSA ER INABA Y ISHIBASHI K NODA M
Citation
Er. Jusa et al., EFFECT OF HEPARIN ON HEMAGGLUTINATION BY AKABANE AND AINO VIRUSES BELONGING TO THE SIMBU GROUP OF BUNYAVIRUSES, Veterinary microbiology, 45(2-3), 1995, pp. 251-258
Citations number
12
Categorie Soggetti
Microbiology,"Veterinary Sciences
Journal title
Veterinary microbiology → ACNP
ISSN journal
03781135
Volume
45
Issue
2-3
Year of publication
1995
Pages
251 - 258
Database
ISI
SICI code
0378-1135(1995)45:2-3<251:EOHOHB>2.0.ZU;2-Q
Abstract
Heparin inhibited the hemagglutinin activity of Akabane and Aino virus es. The minimal inhibitory concentration of heparin required to inhibi t 8 hemagglutination (HA) U of Akabane and Aino viruses was 10 U/ml. G oose erythrocytes failed to combine with the HA inhibitory factor of h eparin. On the other hand, goose erythrocytes treated with heparinase had greatly reduced agglutinability by Akabane virus. Virus-heparin co mplex formation was observed by sedimenting heparin with the virus par ticles.