Background. Women with a first-degree relative with breast cancer are
at increased risk of developing this disease. The optimal medical mana
gement of these women is unclear, with options including close breast
cancer screening, bilateral prophylactic mastectomy, or participation
in chemoprevention trials. Among women who undergo prophylactic bilate
ral mastectomy, very little is known about satisfaction with this surg
ery. Also, we know very little about variables related to prophylactic
mastectomy decision making. Methods. Participants were women at incre
ased risk of breast cancer due to family history. These women were cat
egorized by self-report as not interested in prophylactic mastectomy (
n = 58), interested but deciding against surgery (n = 92), or subseque
ntly having a bilateral prophylactic mastectomy (n = 14). Information
on screening practices, risk. perception, level of depression, and can
cer-related worry was collected. Women completing prophylactic mastect
omy reported on their satisfaction with the surgery and breast reconst
ruction. Results. Women selecting surgery reported more breast cancer
worry. The group expressing no interest in surgery reported fewer biop
sies and lower risk estimates. Women completing surgery were satisfied
with their decision, although satisfaction with reconstruction was mi
xed. Conclusion. Factors influencing surgical decision making may incl
ude breast-cancer-related worry, biopsy history, and subjective breast
cancer risk. (C) 1995 Academic Press, Inc.